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Therapeutic approaches targeting the transcription factor Nrf2 through the PI3K/Akt signaling pathway have been put forward for their anti-inflammatory and antioxidant benefits

doi: 10.22608/APO.2017186 32

doi: 10.1089/neu.2011.1922 105

Interestingly, the presentation of DAPT and BMS appeared to exert the opposite action to TB-500, suggesting that the Notch/NF-B pathways may mediate TB-500s proposed action on angiogenesis

Therefore, in the literature, albumin-corrected IMA index (Albumin X 23 + IMA - 100) is calculated or patients with serum albumin levels below 2 g/dl and above 5.5 g/dl are excluded to prevent interpersonal albumin level changes from affecting the IMA amount